Conference Summary
Protein phosphorylation is one of the most prevalent post-translational modifications governing a wide spectrum of cellular processes and is of paramount significance in the development and homeostasis of adult organisms. Decades of intensive studies have revealed the intricate web of regulatory networks that orchestrate protein phosphorylation in cells and highlighted their remarkable susceptibility to disruption across numerous disease conditions. Protein kinases, the catalysts driving phosphorylation, remain a prime focal point for FDA-approved therapeutics, yet the emergence of drug resistance mechanisms calls for a deeper comprehension of their functionality. Thus, exploring innovative and alternative strategies to control aberrant phosphorylation networks is of critical importance.