Agenda: Understanding Myonuclear Accretion Mechanisms


Conference Organizers:

Doug Millay, PhD, Associate Professor, University of Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

Anita Kneppers, PhD, Postdoctoral Researcher, Institut NeuroMyoGène, Lyon, France

Please note that this tentative schedule is subject to change. 30-minute presentations include 5 minutes of Q & A. 15-minute presentations include 3 minutes of Q & A.

Each speaker will present their talk live, and the presentations' recordings will be accessible to registrants after the sessions, contingent upon speakers who have granted permission.


Day 1

Time (Eastern)Event
9:00 am—9:10 am
FASEB and Organizer Welcome
9:10 am –9:40 am

Shaping Skeletal Muscle Fibres During Early Development
Tim Saunders, PhD, Centre for Mechanochemical Cell Biology, University of Warwick, Coventry, UK

9:40 am—10:10 am

Myoblast and Fibroblast Incorporation to Shape Limb Muscle During Development
Delphine Duprez, PhD, Institut de Biologie Paris, France

10:10 am—10:25 am

p38 Controls the Transition from Myoblast Differentiation to Fusion
Adi Hazak, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel

10:25 am—10:40 am

Real-Time Assay Exposes Myoblast-to-Myofiber Fusion Dynamics
Sharon Havusha-Laufer, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel

10:40 am—10:50 am
10:50 am—11:20 am

Spatial Regulation of Gene Expression in Myofibers
Eric Wang, PhD, Myology Institute of Florida, Gainesville, FL

11:20 am—11:50 am

Chasing Myonuclei Turnover
Minchul Kim, PhD, Institut de Génétique et de Biology Moléculaire et Cellulaire, Strasbourg, France

11:50 am—12:05 pm

Satellite Cell Proliferation is Not Obligatory for Myofiber Fusion During Muscle Hypertrophy
John McCarthy, PhD, Center for Muscle Biology, University of Kentucky, Lexington, KY

12:05 pm—12:20 pm

Murine Skeletal Muscle Nuclei Replicate DNA
Agnieszka K. Borowik, PhD, Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

12:20 pm—12:30 pm
Organizer Wrap-up

 Day 2

Time (Eastern)Event
8:00 am—8:10 am
Organizer Recap of Day 1 and Kickoff
8:10 am –8:40 am

Myofiber Repair After Local Damage
William Roman, PhD, Monash University, Australian Regenerative Medicine Institute, Clayton, Australia

8:40 am—9:10 am

Local Signaling Regulates DNA Content in Skeletal Muscle Nuclei
Mary Baylies, PhD, Memorial Sloan Kettering Cancer Center, New York, NY

9:10 am—9:40 am

The Arp2/3 Complexes: Hidden Role in Skeletal Muscle Postnatal Development and Homeostasis
Silvia Di Francescantonio, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisbon, Portugal

9:40 am—9:50 am
9:50 am—10:20 am

Cellular Senescence and Skeletal Muscle Aging
Nathan K. LeBrasseur, PhD, Mayo Clinic, Rochester, MN

10:20 am—10:50 am

Using Myonuclear Accretion to Generate Mouse Models of Mitochondrial Myopathy
Prashant Mishra, MD, PhD, UT Southwestern Medical Center, Dallas, TX

10:50 am—11:05 am

Characterizing the Role of Sarcalumenin in SR Membrane Remodeling
Ilan Zemski, Dep. of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel 

11:05 am—11:20 am

Neuromuscular Electrical Stimulation Training Induces Myonuclear Accretion and Hypertrophy in Mice Without Overt Signs of Muscle Damage and Regeneration
Julien Gondin, PhD, Institut NeuroMyoGene, PGNM, Lyon, France 

11:20 am—11:30 am
Organizer Closing Remarks