Agenda: Liquid-Liquid Phase Separation

Agenda

Conference Organizer:
Fabrizio Chiti, PhD
Professor of Biochemistry
University of Florence, Florence, Italy

Schedule subject to change. Each speaker will present their talk live, and the entire conference will be recorded.

Time (Eastern)	Event
9:00 am – 9:10 am	FASEB Welcome & Organizer Welcome
9:10 am – 9:40 am	Molecular neuropathology and phenotypic heterogeneity of TDP-43 proteinopathies Manuela Neumann, University of Tübingen, Tübingen, Germany
9:40 am – 10:10 am	Structures of Pathological TDP-43 Filaments in Human Neurodegenerative Diseases Diana Arseni, Medical Research Country, Cambridge, UK
10:10 am – 10:40 am	Small Molecules that Disassemble Pathogenic Amyloid Fibrils David Eisenberg, University of California Los Angeles (UCLA), Los Angeles, CA
10:40 am – 11:00 am	Decoding LLPS: Insights into the Role of Charge Pattern in Protein Phase Separation Greta Bianchi, University of Milan, Bicocca, Italy
11:00 am – 11:20 am	Break
11:20 pm – 11:50 pm	Phase Separation of Full-Length TDP-43 and its Fragments Fabrizio Chiti, University of Florence, Florence, Italy
11:50 pm – 12:20 pm	Kapb2 Mitigates Aberrant Phase Transition and Neuronal Toxicity in C9orf72-ALS/FTD Lin Guo, Thomas Jefferson University, Philadelphia, PA
12:20 pm – 12:50 pm	TDP-43, Anisosomes, Aggregation and Neurodegeneration Don Cleveland, University of California San Diego (UCSD), San Diego, CA
12:50 pm – 1:10 pm	TDP-43 Propagation in iPSCs-derived Cerebral Organoids Yoshitaka Tamaki, Japan
1:10 pm – 1:40 pm	Virtual Roundtable Discussion and Organizer’s Closing Remarks