Please note that all times listed currently reflect US Eastern Time (ET). The schedule is subject to change. Presentations are live or pre-recorded followed by live group Q&A

Day 1: Tuesday, July 27th, 2021

10:00 am – 10:15 amWelcome and Introductions: 
Charles Stephensen (USDA/WHNRC/UC Davis) & Raz Shaikh (University of North Carolina, Chapel Hill)
10:15 am – 11:00 amKeynote Address: Nicole Baumgarth (University of California, Davis)
Regulation of antimicrobial humoral immunity
11:00 am – 11:15 amBreak
11:15 am – 1:00 pmSession 1: Obesity: Impacts on Innate and Adaptive Immunity
Chair: Raz Shaikh (University of North Carolina, Chapel Hill)
11:15 am – 11:35 amAlyssa Hasty (Vanderbilt University)  
Adipose Immunity in Weight Loss and Cycling
11:35 am – 11:55 amDaniel Winer (Buck University)
Insulin Receptor Control of Adaptive Immunity
11:55 am – 12:15 pmArion Kennedy (North Carolina State University)
Unraveling T cell Activation in Obesity Associated Fatty Liver Disease
12:15 pm – 12:35 pmNancie Jo MacIver (Duke University)
Molecular mechanisms of T-cell dysfunction in malnutrition
12:35 pm – 12:45 pmNatalie Harasymowicz (Washington University in St. Louis)
Gene Therapy for fat-1 Prevents Obesity-Induced Inflammation and Cellular Senescence And Increases the Content of Anti-Inflammatory Macrophages
12:45 pm – 1:00 pmQuestions and Answers 
1:00 pm – 2:15 pmBreak
1:15 pm – 2:00 pmMeet the Experts Session 
Room 1 - Setting up and using a gnotobiotic mouse facility for dietary studies. Presentations by Dr. Laxmi Yeruva and Dr. Timothy Hand, followed by discussion.
Room 2 - Using dietary intake data to characterize risk of inflammation. Presentations by Dr. Edward Giovannucci and Dr. Fred Tabung, followed by discussion.
Room 3 - Use of machine learning in nutrition research. Presentation by Dr. Danielle Lemay, followed by discussion.
2:15 pm – 4:00 pmSession 2: Diet and Infection in the Age of COVID
 Chair: Melinda Beck 
(University of North Carolina, Chapel Hill)
2:15 pm – 2:35 pmLinda Saif (The Ohio State University)
Nutritional impacts on immune response to rotavirus infection
2:35 pm – 2:55 pmRaz Shaikh (UNC, Chapel Hill)
Obesity drives a dysregulated specialized pro-resolving mediator signature: Implications for viral infection
2:55 pm – 3:15 pmMelinda Beck (UNC, Chapel Hill)
Obesity and Influenza vaccination: Lessons learned for COVID-19
3:15 pm – 3:35 pmDaniela Frasca (University of Miami)
Obesity, aging, and B-cells
3:35 pm – 3:45 pmSarah Price (University of Louisville)
Got Zinc? A Role for Yersiniabactin in Zinc Acquisition during Yersinia pestis Infection
3:45 pm – 4:00 pmQuestions and Answers
4:00 pm – 4:15 pmBreak
4:15 pm – 5:30 pmPoster Session 1 - Posters will be available online for viewing a few days prior to the virtual SRC; session time will be devoted to Q&A between poster presenters and attendees
5:30 pm – 6:30 pmPlanning the Next Conference - (via zoom link) All conference attendees are invited to discuss plans for collecting feedback on this conference and planning for a future conference.


Day 2: Wednesday, July 28th, 2021

10:00 am – 10:15 amDay Two: Welcome Address and Summary of Day One
10:15 am – 11:45 amSession 3: Nutritional Immunity: The Battle for Nutrients Between Hosts and Bacteria
Chair: Charles Stephensen (USDA, WHNRC/UC Davis)
10:15 am – 10:35 amEric Skaar (Vanderbilt University)
Transition metals and virulence in bacteria
10:35 am – 10:55 amManuela Raffatellu (University of California, San Diego)
Nutritional Immunity in the inflamed gut
10:55 am – 11:15 amHal Drakesmith  (University of Oxford)
The battle for iron: A key determinant of the outcome of infection
11:15 am – 11:25 amJeanette Miller (Vanderbilt University)
The Function of a Bacterial Lytic Transglycosylase in Mitigating Zinc Dysregulation
11:25 am – 11:45 amQuestions and Answers
11:45 am – 12:00 pmBreak
12:00 pm – 1:45 pmSession 4: Diet, Microbiome, and Immunity During Infancy 
Chair: Sarah Comstock (Michigan State University)
12:00 pm – 12:20 pmTimothy W. Hand (University of Pittsburgh)
The role of maternal IgA in infant gut health
12:20 pm – 12:40 pmLaxmi Yeruva (Arkansas Children's Nutrition Center)
Breastmilk and immunity in the infant: Lessons from animal models
12:40 pm – 1:00 pmMarcia Monaco (University of Illinois)
A swine model of colitis for mechanistic understanding of microbiota and immunity
1:00 pm – 1:20 pmValerie Verhasselt (University of Western Australia)
Antigen shedding in human milk: a key for immune system education
1:20 pm – 1:30 pmAkila Rekima (University of Western Australia)
Colostrum drives the development of successful anti-helminth immune defenses
1:30 pm – 1:45 pmQuestions and Answers
1:45 pm – 3:00 pmBreak
2:00 pm – 2:45 pmCareer Development Session for Early Career Scientists - Two senior scientists (Drs. Stephen Hursting and Charles Stephensen) and two mid-career scientists (Drs. Raz Shaikh and Sarah Comstock) discuss how to succeed in a scientific career.
3:00 pm – 3:45 pmPoster Session 2 - Posters will be available online for viewing a few days prior to the virtual SRC; session time will be devoted to Q&A between poster presenters and attendees
3:45 pm – 4:00 pmBreak
4:00 pm – 5:45 pmSession 5: Prebiotics, Probiotics and Immune Health
 Chair: Margherita Cantorna 
(Penn State University)
4:00 pm – 4:20 pmSarah Comstock (Michigan State University)
Prebiotic dietary modifications to decrease intestinal inflammation in adult humans
4:20 pm – 4:40 pmMargherita Cantorna (Penn State University)
Mechanisms underlying vitamin D control of mucosal infection
4:40 pm – 5:00 pmAdam Moeser (Michigan State University)
Early nutrition, stress, the microbiome, and intestinal mast cell function
5:00 pm – 5:20 pmDanielle Lemay (USDA, Western Human Nutrition Research Center/UC Davis)
Dietary fiber, microbiome and intestinal inflammation in healthy humans
5:20 pm – 5:30 pmYasmine Bouzid (University of California, Davis)
Adequate intake of dietary fiber is associated with lower gastrointestinal inflammation in healthy U.S. adults
5:30 pm – 5:45 pmQuestions and Answers


Day 3: Thursday, July 29th, 2021

10:00 am – 10:15 amDay Three: Welcome Address and Summary of Day Two
10:15 am – 11:00 amKeynote Address: Stephen Hursting (UNC, Chapel Hill)
Breaking the Obesity-Cancer Link: A Mechanistic Perspective
11:00 am – 11:15 amBreak
11:15 am – 1:00 pmSession 6: Environmental and Nutritional Stressors on Immunity 
Chair: Simin Meydani (USDA/ HNRCA/Tufts University)
11:15 am – 11:35 amCheryl Rockwell (Michigan State University)
The food preservative tert-butylhydroquinone exacerbates the T cell response to food allergen
11:35 am – 11:55 amMichael B. Fessler (National Institute of Environmental Health Sciences)
Oxysterols Coordinate Lipid and Inflammatory Homeostasis in the Lung
11:55 am – 12:15 pmPhilip Calder (University of Southampton)
n-3 PUFA and adaptive immunity in humans
12:15 pm – 12:35 pmKym Gowdy (The Ohio State University)
Dietary Omega-3 Polyunsaturated Fatty Acids Modulate the Pulmonary Response to Environmental Exposures
12:35 pm – 12:45 pmJerry Lio (Ohio State University)
Vitamin C Potentiates Plasma cell Differentiation via TET-mediated DNA Modifications at a Novel Prdm1 Distal Element
12:45 pm – 1:00 pmQuestions and Answers
1:00 pm – 2:00 pmBreak
1:15 pm – 1:45 pmSponsored Event (National Dairy Council) - Dr. Chris Cifelli, VP for Research, will describe the Council's program for research funding and provide an overview of recently funded projects related to diet and inflammation.
2:00 pm – 3:45 pmSession 7: Dietary Patterns, Microbiota, Inflammation/Immunity and Disease Risk
Chair: Jimmy Crott (USDA/Human Nutrition Research Center on Aging/Tufts University)
2:00 pm – 2:20 pmFred Kinyuy Tabung (The Ohio State University)
Dietary indices of inflammation and cancer risk
2:20 pm – 2:40 pmEdward Giovannucci (Harvard University)
Inflammatory diets, microbiome and colon cancer risk
2:40 pm – 3:00 pmCharles Stephensen (USDA, WHNRC/UC Davis)
Association of Healthy Eating Index scores with inflammation and immune activation in healthy adults
3:00 pm – 3:20 pmStine M. Ulven (University of Oslo)
Dietary fat, metabolomics and inflammation assessed by gene expression profiling
3:20 pm – 3:30 pmQi Jin (The Ohio State University)
Hyperinsulinemic and pro-inflammatory dietary patterns are associated with increased risk of total and site-specific cancers among postmenopausal women
3:30 pm – 3:45 pmQuestions and Answers
3:45 pm – 4:00 pmBreak
4:00 pm – 5:30 pmSession 8: Diet, Intestinal Inflammation and Cancer
 Chair: Stephen Hursting 
(UNC, Chapel Hill)
4:00 pm – 4:20 pmJimmy Crott (USDA, HNRCA)
Dietary fat, microbiome, inflammation and intestinal tumorigenesis
4:20 pm – 4:40 pmConnie Rogers (Penn State University)
Role of changes in energy balance and related nutritional factors on inflammation
4:40 pm – 5:00 pmBill Murphy (UC Davis)
Effect of obesity-related inflammation on immunotherapy in cancer
5:00 pm – 5:10 pmMichael Coleman (UNC Chapel Hill)
β-Hydroxy-β-Methylbutyrate synergizes with cytotoxic chemotherapy and immunotherapy in a mouse model of pancreatic cancer
5:10 pm – 5:30 pmQuestions and Answers
5:30 pm – 5:45 pmWrap-up by Conference Organizers