November 8, 2023
Terminally differentiated neurons are non-proliferating, long-lived cells with high metabolic activity. As a result, they must deal with a considerable DNA damage burden. The way neurons cope with DNA damage differs strikingly from mitotic or cycling cells. Recent studies highlight how DNA damage and dysfunctional DNA repair may contribute to neurodegenerative diseases. Yet it is not clear whether genome instability is a primary driver of neuronal loss or an epiphenomenon.
Join FASEB for this informative online conference, which will bring together experts to discuss recent discoveries in DNA damage and repair for neurodegenerative diseases.
Aris Polyzos, PhD, Research Scientist, Lawrence Berkeley National Laboratory, Berkeley, CA
Laurie Sanders, PhD, Associate Professor, Duke University School of Medicine, Durham, NC