2018 BioArt Winners


Parinaz Fathi; Neal Mistry; Tor Jensen, PhD; Brad Sutton, PhD; and Dipanjan Pan, PhD

University of Illinois at Urbana-Champaign

Title: 3D Image of a Human Heart

Research focus: Cardiovascular research

This image depicts a 3D-printed heart which was based on an MRI image taken of a patient's heart. The use of 3D models is one example of how medical care can be made more interactive and understandable for patients.

Funding: National Physical Science Consortium Graduate Fellowship, National Institute of Standards & Technology GMSE Fellowship

Carolyn Tam, MSc

Imperial College London

Title: 3D Image of Bio-receptive Panels Infused with Living Bacterial Cellulose Fibers

Research focus: Bioreceptive structure for bacterial cellulose

The image shows how biological fabrication can be integrated with bio-receptive materials. These panels are infused with bacterial cellulose fibers, which will ultimately grow, evolve, and respond to their environment, turning buildings into a living infrastructure.

Michael Chaise Gilbert

University of Massachusetts Amherst 

Title: Zebrafish Skeletal Image Showing Bone and Cartilage

Research focus: Anatomy

This image of a zebrafish (Danio rerio) shows the bone (green) and the cartilage (red) that comprises the skeleton. Researchers are using this image, and ones like it, to better identify how a mutation in the primary cilia can affect skeletal development, structure, and morphology.

Funding: National Science Foundation, Division of Integrative Organismal Systems

Jodi A. Hadden, PhD

University of Delaware, Newark 

Title: The Capsid of the Hepatitis B Virus

Research focus: Computational virology

The hepatitis B virus (HBV) packages its genome in an icosahedral protein shell called a capsid (depicted here). Eberhard’s theorem indicates that a capsid must contain 12 pentamers to form a closed shell (upper left). The HBV capsid is composed of 12 pentamers and 30 hexamers (lower left). The triangulation number of the capsid, T=4, indicates that there are four unique positions that constituent proteins can occupy (upper right). There are a total of T*60=240 proteins, altogether 120 dimers, that make up the HBV capsid (lower right).

Casey Holliday, PhD

University of Missouri School of Medicine, Columbia 
Member: American Association of Anatomists, Society for Vertebrate Paleontology​

Title: Human Hand Showing Carpal Tunnel Tendons and Palm Muscles

Research focus: Comparative biomechanics and evolutionary medicine

This is an image of a human hand showing the tendons of the carpal tunnel and intrinsic muscles of the palm. The human hand is one of our finest adaptations. Researchers are using this image to determine 3D architecture of muscles to better understand how our hands work and how they've changed over time.

Zachary Randall, MS; Larry Page, PhD; and David Blackburn, PhD

Florida Museum of Natural History, University of Florida, Gainesville

Title: CT Scan Reconstruction of an Angler 

Research focus: Anatomy

This CT scan reconstruction of the Angler, Lophius piscatorius (UF 118531) from the Florida Museum of Natural History fish collection shows the complex osteology of a popular food fish. The colorized CT reconstruction shows change in density. The brighter colors represent elements with higher density and the darker colors represent elements with lower density.

Funding: National Science Foundation (DBI-1701714)

Marisol O’Neill,* Gene Huang,* and Dolores J. Lamb, PhD**

Baylor College of Medicine, Houston, TX

** Weill Cornell Medicine, New York, NY
Member: Endocrine Society​

Title: Micro CT Images of the Murine Penis

Research focus: Reproductive biology, urogenital development

This image depicts micro CT images of the murine penis. Micro CT imaging has enhanced researchers' ability to study urogenital abnormalities.

Funding: National Institute of Diabetes and Digestive and Kidney Diseases

Sardar Pasha Sheik Pran Babu

Indiana University School of Medicine, Indianapolis
Member: American Society for Pharmacology and Experimental Therapeutics​

Title: Mouse Retina That Underwent Vascular Pathology

Research focus: Developmental biology – retinal vascular biology

This high-resolution fluorescence image depicts a mouse retina that underwent vascular pathology. Researchers are using this image to explore how the vascular pathology can be cured in the diseased condition using mouse in vivo models.

Amy Engevik, PhD

Vanderbilt University Medical Center, Nashville, TN
Member: The American Physiological Society

Title: Intestinal Villi of a Mouse

Research focus: Gastrointestinal research

The micrograph shows intestinal villi of a mouse. The immunofluorescence staining depicts the brush border (seen in pink/magenta) that is responsible for the absorption of water and nutrients that are essential for life. Scientists are using mouse models to better understand the components necessary to maintain homeostasis. This knowledge is critical to ameliorate gastrointestinal disorders and pathogenic infections.

Funding: National Institute of Diabetes and Digestive and Kidney Diseases

Crystal D. Rogers, PhD,* and Mariano Loza-Coll**

California State University, Northridge
* Member: Society for Developmental Biology

** Member: Genetics Society of America

Title: Stained Fruit Fly Ovary

Research focus: Gastrointestinal research

This image depicts a fruit fly ovary stained for cytoskeleton (magenta) and DNA (blue) and expressing GFP in cells that respond to STAT proteins (yellow). Researchers are using this experiment and image to demonstrate molecular biology techniques to undergraduate researchers.

Funding: Rogers, National Institute of Child Health and Human Development (R15 HD092170 01); Loza-Coll, National Institute of General Medical Sciences (SC2 GM125573 01)

Lu Yang;* David Ornitz, MD, PhD;* and Sung-Ho Huh, PhD**

* Washington University School of Medicine, St. Louis, MO
Members: Society for Developmental Biology

** University of Nebraska Medical Center, Omaha
Member: Society for Developmental Biology

Title: Mouse Nasal Cavity Showing the Olfactory Epithelium

Research focus: Developmental biology

This image depicts the inside of the mouse nasal cavity showing the olfactory epithelium, the tissue responsible for the sense of smell. The olfactory epithelium, in green, overlies the interior walls of the nasal cavity as well as the surfaces of turbinates, which are bony scrolls projecting inward from the nasal cavity wall.

Funding: National Heart, Lung, and Blood Institute

Jing Yang, PhD, and Sharon Stack, PhD

University of Notre Dame, IN
Members: American Society for Biochemistry and Molecular Biology​

Title: Adhesive Structures on Surface of Ovarian Cancer Cells

Research focus: Cancer research

This scanning electron micrograph depicts adhesive structures on the surface of ovarian cancer cells. Researchers are using this image to investigate mechanisms of cancer cell adhesion.

Funding: National Cancer Institute

Tanveer Ahmed and Andres Buonanno

National Institutes of Health, Bethesda, MD

Title: Video Imaging of Human Embryonic Kidney Cells

Research focus: Cancer research

Live cell imaging of human embryonic kidney (HEK-293) cells which were transfected with a Neuregulin3 (NRG3) construct harboring green fluorescent protein tag. Cells were imaged 16 hours post-transfection using airy scan microscope (Zeiss). The video depicts endocytosis of NRG3 in HEK-293 cells.

Funding: National Institute of Child Health and Human Development intramural grant

Nathanaël Prunet, PhD;* Elliot Meyerowitz, PhD;** and Luciano Lucas, PhD***

University of California, Los Angeles; California Institute of Technology, Pasadena; and Howard Hughes Medical Institute

** California Institute of Technology, Pasadena, and Howard Hughes Medical Institute
Member: Society for Developmental Biology, Genetics Society of America​

*** DRVISION Technologies, Bellevue, WA

Title: Video of Arabidopsis flowers forming at tip of stem

Research focus: Developmental biology

This video shows young Arabidopsis flowers forming at the tip of the stem, imaged with a confocal microscope, with cells expressing the SHOOT MERISTEMLESS gene in green. We use microscopy to study the formation of flowers, and the genes and hormones that control this developmental process.

Funding: National Institute of General Medical Sciences (R01 GM104244)

Maria Voigt

RCSB Protein Data Bank, Rutgers University, Piscataway, NJ

Title: Video of Calcium Pump in Action

Research focus: Structural biology

Atomic structures have captured the calcium pump in action, a protein that transports calcium ions from muscle cell cytoplasm to the sarcoplasmic reticulum after each muscle contraction. The pump is powered by adenosine triphosphate and aided by magnesium.

Funding: National Science Foundation, National Institutes of Health, and US Department of Energy