This FASEB SRC will focus on virus assembly, virus structure, and structure-based mechanisms of virus replication (entry, replication, virus-host interactions). Studies in these areas provide insight into a multitude of cellular processes from the perspective of relatively simple and relatively easy to manipulate organisms, viruses and bacteriophages. Moreover, these cellular processes are critical for the pathogenicity of infectious viruses and therefore are targets for established and novel antiviral therapeutics. Many new therapies are a direct result of basic scientific investigations, which have been the emphasis of past FASEB Virus Structure and Assembly conferences.
This SRC will integrate viral genomics, molecular virology, biophysical virology, and structural virology. Invited speakers will showcase diverse approaches to study virus assembly and structure, viral replication, entry into host cells (infection) the interactions and co-evolution between viruses and hosts, and the deep connections between viruses from all kingdoms of life. The meeting will address recent developments in the area of structure determination, such as in single particle electron-microscopic image reconstruction, tomography and asymmetric reconstruction where advances continue to be rapid and exciting. The use of viruses as biomedical and biotechnological tools, and their overall evolutionary trajectories will be featured sessions. Viral genetics, cell biology, and molecular biology will round out this multi-faceted meeting. The diversity of the scientific program and the ample opportunity for interactions among attendees encourages the development of new cross-disciplinary collaborations.
Submitted abstracts will be considered for short talks. A poster competition, a dedicated session for graduate student talks, and Meet the Expert sessions at meals will provide graduate students and postdoctoral fellows abundant opportunities for meaningful interactions. Travel funds are expected to be available on a competitive basis for trainees and young investigators.