This FASEB SRC will bring together a wide range of scientists and physicians studying the direct impact of trace elements on human health, nutrition, and disease. Trace elements such as iron, copper, zinc, manganese, selenium, and molybdenum are essential for life. However, inappropriate handling of these essential trace elements can result in cytotoxicity. Trace element toxicity can result from redox active elements promoting the formation of damaging reactive oxygen species or by the inactivation of critical enzymes by mis-incorporation of the incorrect cofactor. Considering ~30 % of the proteins encoded by the human genome bind metal cofactors, it is of fundamental importance to understand the partitioning and delivery of these elements. The aim of the 2018 FASEB Trace Elements in Biology and Medicine meeting is to bring together a broad range of scientists studying the roles of essential trace elements in nutrition, health, and medicine, with the goals of advancing our understanding of how cells and organisms balance trace element acquisition, distribution, utilization, trafficking, and storage, with the metabolic demand for each trace element.
This SRC will include keynote presentations, research and poster talks, and informal research discussions. Many short talks will be selected from the submitted abstracts. Session topics include trace element transport and homeostasis, trace elements and host pathogen interactions, trace elements in human disease, imaging, quantifying and sensing trace elements, signaling and regulation, cofactor assembly and trafficking, trace elements in model systems, and new aspects of trace element metabolism. Oral presentations within the sessions will include research using microbes, plants, and animals, as well as applied research studying the roles of trace elements in human nutrition, immunity, development, and disease.
Trainees are highly encouraged to attend this at this meeting. The conference schedule includes multiple events aimed at enhancing the training of the next generations of scientists, including a career and mentoring workshop, “meet the experts” sessions, and a poster blitz, which provides a platform for graduate students and new post-doctoral researchers to make a critical conference wide first impression and highlight their poster. Importantly, there will be many opportunities for informal interactions with international leaders in a relaxed setting to maximize the exchange of information, stimulate multi-disciplinary collaborations, and to provide opportunity for trainees and junior faculty to interact with the current leaders in the field.