Protein Phosphatases

Conference Summary

This FASEB SRC focuses on protein phosphatases, essential components of phosphorylation-based regulatory networks, which control virtually all biological processes. This is an exciting time in protein phosphatase research. New insights into the actions of individual protein phosphatases are being directly connected to pathophysiological outcomes, and phosphatase-directed therapeutics are in rapid development.

This conference unites a dynamic international community of researchers from all levels of academia and industry around shared interests in phosphatases, while highlighting diverse perspectives and approaches to their study: from basic to translational research, and from cell and systems biology to biochemistry and structural biology. The program will link detailed understanding of phosphatase structure and mechanism to control of basic cellular processes, i.e. cell proliferation, migration and metabolism, in healthy and diseased cells. Recent successes in therapeutic targeting of phosphatases will be highlighted.

Conference sessions will explore new methods for investigating protein phosphatases and their signaling networks, and will highlight the latest discoveries concerning phosphatases that target phosphothreonine, phosphoserine, phosphotyrosine or phosphohistidine residues. Recent findings reveal new roles for these enzymes in regulating basic metabolic and cell biological processes in the nervous and immune systems. A major focus for the meeting is elucidating protein phosphatase function and perturbation in disease especially cancer. Drug development efforts to treat cancer, auto-immune and neurodegenerative disorders, and diabetes by either activating or inhibiting phosphatases will be discussed. The conference will highlight new areas of investigation, and researchers that are new to the field or want to educate themselves about these enzymes are encouraged to attend. The meeting will take place in Snowmass, Colorado, a beautiful setting that promotes both formal and informal interactions between conference attendees.

Dr. Nick Tonks, who discovered phosphotyrosine phosphatases thirty years ago and continues to lead breakthroughs in their study, will deliver the conference’s keynote address. Platform and poster sessions will cover the latest in phosphoproteomic, systems and structural studies of phosphatases, emerging research in their regulation of gene expression, cell division cycle and cytoskeleton, and investigations of phosphatase function in different physiological contexts ranging from hematopoietic cells to neurons.  Invited presentations given by experts in the field, will be combined with short talks chosen from submitted abstracts. Meet the expert sessions and a career development event are offered to stimulate interactions between senior and junior investigators.

Important Deadlines:

  • Early bird registration deadline May 21, 2018
  • Last day to register June 13, 2018


  • Short talks chosen from submitted abstracts will incorporate late-breaking results
  • Keynote address by Nick Tonks celebrates the 30 year anniversary of tyrosine phosphatase discovery
  • Therapeutic targeting of phosphatases session will highlight recent successful drug development efforts

Keynote Speaker

Nicholas Tonks, PhD
Cold Spring Harbor Laboratory

Conference Organizers

Martha S. Cyert, PhD
Stanford University

Co-Chair: Nunzio Bottini, MD, PhD
University of California San Diego

FASEB Conference Staff

Robin Crawford, CMP, Conference Manager

Contact us

Email: src@faseb.org
Phone: 1.301.634.7010

Date & Location


July 15-20, 2018


Base Village Conference Center
110 Carriage Way
Snowmass Village, CO

Transportation & Lodging

Airport Information

The closest airport is Aspen/Pitkin Airport, which is 20 minutes from Snowmass Village.  If you fly into this airport, your Snowmass hotels will offer complimentary shuttle service to and from the airport and your hotel.

If you fly into Denver, Colorado Mountain Express (CME) is the official shuttle service to and from Denver International Airport for the FASEB Science Research Conferences. 

Please refer to the GROUP CODE: FASEB for the discounted rate of $97.00 one-way. View shuttle rate details. To make reservations, call the reservation center at: 
1.800.525.6363 (with the United States) 
970.926.9800 (outside the United States)

Click the links below for Transportation & Lodging information:

Official Conference Lodging

Stonebridge Inn
300 Carriage Way
Snowmass Village, CO
Pokolodi Lodge
25 Daly Ln
Snowmass Village, CO

If you request a single or a double occupancy room, the registration fee covers 5 nights of lodging (Sunday through Thursday night, checkout Friday morning). A credit card will be required upon check-in for incidental expenses (i.e. in-room movies, room service, etc.).

If you plan to arrive early or stay beyond the conference dates, you must make your own reservations for the extra nights you require. You are responsible for payment upon check-out.

Click here for additional Offsite Lodging.

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