Machines on Genes

Conference Summary

This FASEB SRC will unite scientists pushing the boundaries of our molecular understanding of the nucleic acid transactions which facilitate life. Information encoded in RNA and DNA is accessed, maintained, decoded and degraded by a staggering number of proteins, protein/DNA and protein/RNA complexes that catalyze specific fundamental enzymatic reactions which drive nucleic acid transactions— not limited to, but including key cellular processes such as DNA replication and repair, recombination, transposition, transcription, translation and epigenetic gene regulation. These protein and RNA machines are impacted in varying disease states, and can be exploited for therapeutic advantage including using CRIPSR gene editing technologies. The use of emerging biophysical methodologies such as single-molecule spectroscopy/microscopy and small-angle X-ray scattering, cryo electron microscopy, and chemical biology has opened new doors to exploration of nucleic acid metabolism. This meeting will highlight exciting efforts underway to decipher the anatomy, architecture and mechanisms of these protein and protein-nucleic acid machines in order to understand how they recognize, engage, and manipulate the structure of DNA and RNA. We aim to unite established and future leaders in the field to exchange ideas and formulate new collaborations. We highly encourage student, postdoctoral trainees, and young investigators to attend, and will encourage their attendance with student and postdoc travel scholarships and a large number of oral presentations, to be selected from the abstracts. Selected talks, poster presentations, and recreational activities will present students and postdoctoral fellows with both formal and informal networking opportunities. Additional organized "meet the experts" panel discussions will help junior colleagues navigate various topics related to careers and women in science. This exciting program will facilitate cross-talk between multiple areas of science, techniques, and skill levels to inspire new innovations and quality science in the area of nucleic acid structural and mechanistic biology.

Important Deadlines:

  • Early bird registration deadline April 30, 2018
  • Last day to register May 23, 2018


  • Invited lectures illuminating cutting edge research on the molecular mechanisms of governing DNA and RNA transactions.
  • Short talks highlighting late breaking data chosen from submitted abstracts.
  • Scientific networking and collaboration through a "meet the experts" discussion forum, nightly poster sessions and "poster flashes”.
  • Organized hiking and rafting excursions.

Keynote Speakers

Eva Nogales PhD
University of California, Berkeley, HHMI

Zhang Xiaodong, PhD
EMBO Keynote Lecture
Imperial College London

Conference Organizers

Katrin Karbstein, PhD
The Scripps Research Institute

Scott Williams, PhD

Jens Michaelis, PhD
Ulm University

FASEB Conference Staff

Robin Crawford, CMP, Conference Manager

Contact us

Email: src@faseb.org
Phone: 1.301.634.7010

Date & Location


June 24-29, 2018


Base Village Conference Center
110 Carriage Way
Snowmass Village, CO

Transportation & Lodging

Airport Information

If you fly into Denver, Colorado Mountain Express (CME) is the official shuttle service to and from Denver International Airport for the FASEB Science Research Conferences. 

Please refer to the GROUP CODE: FASEB for the discounted rate of $97.00 one-way. View shuttle rate details. To make reservations, call the reservation center at: 
1.800.525.6363 (with the United States) 
970.926.9800 (outside the United States)

Click the links below for Transportation & Lodging information:

Official Conference Lodging

Stonebridge Inn
300 Carriage Way
Snowmass Village, CO
Pokolodi Lodge
25 Daly Ln
Snowmass Village, CO

If you request a single or a double occupancy room, the registration fee covers 5 nights of lodging (Sunday through Thursday night, checkout Friday morning). A credit card will be required upon check-in for incidental expenses (i.e. in-room movies, room service, etc.).

If you plan to arrive early or stay beyond the conference dates, you must make your own reservations for the extra nights you require. You are responsible for payment upon check-out.

Click here for additional Offsite Lodging.

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