Reversible Acetylation on Health and Disease (HDACs)

Conference Summary

Over the past few years, the “epigenetic” regulation of the genome has become increasingly important to understanding both the etiology and fundamental mechanisms of aging and age-related diseases.  Key to epigenetic regulation are two classes of lysine-modifying enzymes, the histone deacetylases (sirtuins and HDACs) and the histone acetyltransferases (HATs).

This SRC is the only conference dedicated to protein acetylation, and will bring together leaders in the field to exchange exciting new fundamental discoveries such as new lysine post-translational modifications (e.g. 3-hydroxybutyryl lysine and palmitoyl lysine) and the how these modifications can regulate transcription, cell signaling, and protein secretion. 

A primary objective of the conference is to transfer knowledge and foster collaboration between basic academic researchers, clinical scientists, and industrial researchers to understand how lysine acetylation controls human health and how to prevent and treat a diverse set of age-related diseases that could extend human healthspan and lifespan.  A second objective is to foster the development and interests of younger investigators to help support their career development.  This meeting is particularly timely because recent development on bromodomain inhibitors is continuing to generate a lot of interests and more clinical data on small molecule modulators of sirtuins and HDACs are being generated. 

Program Agenda

Important Deadlines:   Early Bird: June 25, 2017         Last Day to Register: July 23, 2017


  • Career Development Workshops
  • Keynote Speaker: Robert Roeder, The Rockefeller University “Mechanisms Involved In Cooperative Functions Of Histone Acetyltransferases”
  • Panel discussion: Terry Sheppard (Nat. Chem. Biol. Editor), Philip Cole, James Ellis (GSK), Lisa Monteggia “Career Choices”
  • Meet the Expert sessions

Keynote Speaker

Robert Roeder
The Rockefeller University

David Sinclair
Harvard University

Conference Organizers

Li-Huei Tsai
Massachusetts Institute of Technology

Hening Lin
Cornell University, HHMI

Yingming Zhao
The University of Chicago

Conference Staff

Robin Crawford, CMP, Conference Manager

Pippa O'Shea, Conference Assistant

Contact us:
Email: src@faseb.org
Phone: 1.301.634.7010

Date & Location

Date: August 6-11, 2017
Mountain Mall, Mammoth Room

50 Big Sky Resort Road
Big Sky, MT

Transportation & Lodging

Airport Information

The closest airport to the Big Sky area is the Bozeman Yellowstone International Airport (BZN). The lodge is approximately one hour from the airport. Please visit the BZN site for more information.

Shuttle Service and car rentals are available. Please use the link below for Transportation & Lodging information:

Official Conference Lodging

Big Sky Resort
Huntley Lodge
50 Big Sky Resort Road
Big Sky, MT 

Guest rooms are reserved for attendees at the Huntley Lodge. All rooms have a private bath, free WiFi, high definition TV, coffee maker, refrigerator, and seating area. Rooms do not include air conditioning. Onsite amenities include a spa, fitness center, tennis courts and outdoor pool.

If you request a single or a double occupancy room, the registration fee covers 5 nights of lodging (Sunday through Thursday night, checkout Friday morning). A credit card will be required upon check-in for incidental expenses (i.e. in-room movies, room service, etc.).

If you plan to arrive early or stay beyond the conference dates, you must make your own reservations for the extra nights you require. You are responsible for payment upon check-out.

Click here for additional Offsite Lodging.