Regulation and Function of Small GTPases

Conference Summary

This SRC provides an interactive forum that covers the latest developments in the small GTPase field and presents the newest technological advancements that are being used to unravel the complex roles of small GTPases in human health and disease. Small GTPases (e.g. Ras, Rac, Rho, Cdc42, Rab, Rap, Rheb and Ral) are essential for key cellular processes such as cell differentiation, proliferation, and migration, as well as the regulation of subcellular events such as vesicle trafficking. These critical functions of small GTPases make them important participants in a wide variety of physiological and pathophysiological processes. The founding member of the small GTPase superfamily, Ras, is the most commonly mutated oncogene in human cancers, and many other small GTPases (including RhoA, Rac1, Rab5, Rheb, and RalA) also play fundamental roles in cancer development and progression. Due to these important oncogenic functions of small GTPases, there is a strong cancer theme underlying this meeting. However, small GTPases also participate in other biomedically important events, including the promotion of vascular diseases, immunological abnormalities, mental disorders, and metabolic conditions. For these reasons, progress from a number of fields in addition to cancer biology will be highlighted, including neurobiology, developmental biology, computational biology, and membrane biophysics to ensure that we are leveraging and learning from discoveries made in important related fields. The main objective of the meeting is to stimulate cross-pollination of ideas among researchers investigating basic biochemical mechanisms, cell and tissue biology, and translational models to define the diverse functions of small GTPases.

This SRC has been one of the premier meetings in the field of small GTPases for the last 25 years. There will be the opportunity for oral and poster presentations and social and recreational activities will provide all registrants with opportunities to exchange ideas and formulate new collaborations. It is anticipated that there will be funds available to support minority and female applicants at early stages of their careers.

Program Agenda

Important Deadlines:    Early Bird: May 3, 2017      Last Day to Register: May 11, 2017


  • Short talks selected from submitted abstracts
  • "Meet-the-Expert" session
  • Career-Oriented workshops for trainees and early-career investigators

Keynote Speaker

Prof. Allan Balmain
University of California San Francisco Helen Diller Family Comprehensive Cancer Center

Conference Organizers

Dr. Carol Williams
Medical College of Wisconsin

Dr. Angeliki Malliri
Cancer Research UK Manchester Institute

Conference Staff

Kristen Hagy, CMP, Conference Manager

Pippa O'Shea, Conference Assistant

Contact us:
Email: src@faseb.org
Phone: 1.301.634.7010

Date & Location

Date: June 11-16, 2017
Marriott West Palm Beach
1001 Okeechobee Boulevard
West Palm Beach, FL

Transportation & Lodging

Airport Information

Palm Beach International Airport (PBI) is less than 3 miles from the West Palm Beach Marriott.  Fort Lauderdale airport (FLL) is one hour away.

West Palm Beach Marriott Complimentary Airport Shuttle service to/from the airport is available. Use the courtesy phone located in the baggage claim area to contact the hotel for transfer to the hotel.  Shuttle hours are 6 a.m. - midnight.  

Click the links below for Transportation & Lodging information

Official Conference Lodging

Marriott West Palm Beach
1001 Okeechobee Boulevard
West Palm Beach, FL 33401-6214

If you request a single or a double occupancy room, the registration fee covers 5 nights of lodging (Sunday through Thursday night, checkout Friday morning). A credit card will be required upon check-in for incidental expenses (i.e. in-room movies, room service, etc.).

If you plan to arrive early or stay beyond the conference dates, you must make your own reservations for the extra nights you require. You are responsible for payment upon check-out.

Click here for additional Offsite Lodging.