Small GTPases in Membrane Processes: Trafficking, Autophagy and Disease

Conference Summary

The fields of membrane trafficking in general and autophagy in particular got the Nobel Prize for Medicine in 2013 and 2016, respectively.  This work laid the foundation for understanding these processes at a mechanistic detail and high precision.  The question of how membrane structure and function is regulated is highly relevant to human health and disease.

Regulation of membrane-associated processes is a very dynamic field relevant to various disciplines, from neuroscience to cell and developmental biology.  Small GTPases have emerged as important regulators of all membrane trafficking processes. These GTPases together with their various interactors regulate intracellular trafficking, organelle dynamics, proteostasis, signaling and metabolism. Mutations in these molecules result in human diseases, from inherited to complex disorders. For example, dis-regulation of small GTPase networks has been implicated in multiple diseases, including cancer and neurological disorders. 

The aim of this conference is include all the small GTPase families involved in membrane processes, i.e., Arf, Arl, Rab, Ras, Rho and Rag, and explore new insights into their cellular function.  The vision is to obtain an integrated view of their functions and their networks. We will discuss new emerging concepts derived from a variety of experimental systems, ranging from cells to organisms. We will explore new discoveries from studies of human diseases.  Finally, because we think the field will benefit from interdisciplinary approaches, our goal is to include various emerging technologies. In addition to the traditional cell and molecular biology, the conference will include advanced light and electron microscopy, structural biology, structure-function and physico-chemical analyses, single-molecule and other biophysical techniques, and mathematical modeling.

View the full list of speakers and share with your lab!

Important Deadlines:

  • Early bird registration deadline Aug 6, 2018
  • Last day to register August 22, 2018


  • "Meet the Experts” session

  • Career-orientated Workshops, "Mathematical Modeling in Cell Biology" and "Biomedical Research Workforce Development"

  • Short talks selected from abstracts and two minute poster preview talk

Keynote Speakers

Dafna Bar-Sagi

The EMBO Keynote Lecture
Wolfgang Baumeister
Max-Planck-Institute of Biochemistry (Germany)

Conference Organizers

Nava Segev

Marino Zerial

FASEB Conference Staff

Silvy Song, Conference Manager

Contact us

Email: src@faseb.org
Phone: 1.301.634.7010

Date & Location


September 23-28, 2018


The National Conference Center
18980 Upper Belmont Place
Leesburg, VA 20176

Transportation & Lodging

Airport Information

Washington Dulles International Airport (IAD) is approximately 14 miles or 21 minutes from the National Conference Center. 

Click the links below for Transportation & Lodging information

Official Conference Lodging

The National Conference Center
18980 Upper Belmont Place
Leesburg, VA 20176

A credit card will be required upon check-in for incidental expenses (i.e. in-room movies, room service, etc.)

If you plan to arrive early or stay beyond the conference dates, you must make your own reservations for the extra nights you require. You are responsible for payment upon check-out.

Click here for additional Offsite Lodging.

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