Biological Methylation: Fundamental Mechanisms in Human Health and Disease

Conference Summary

This FASEB SRC focuses on recent advances in our understanding of the role of dynamic methylation of proteins, DNA, and RNA in diverse nuclear and cytoplasmic biological processes and how this modification impacts epigenetic cellular identity, tissue homeostasis, development, and the pathogenesis of human diseases. Since methylation has become a major therapeutic target in recent years, the development of epigenetic-based medicines that target methyltransferase, demethylase, and methylation readers for the treatment of cancer and other diseases will be a topic covered in the program.

This meeting will bring together an interdisciplinary group of scientists interested in how a small covalent modification can have such profound biological impact.  Invited speakers are experts in protein, DNA and RNA methylation from a variety of perspectives including epigenetics and epigenomics, molecular biology, cell and developmental biology, cancer biology, structural biology and chemical biology.  The conference will be structured to optimize interactions among all attendees, with several poster sessions and technology workshops. A significant number of oral presentations will be chosen from poster abstracts submitted by trainees and junior faculty.  This conference will also be an excellent opportunity for scientists less familiar with methylation mediated signaling and epigenetics to learn how this rapidly evolving field could impact their research.

Important Deadlines:

  • Early bird registration deadline April 23, 2018
  • Last day to register May 3, 2018


  • Survey of the latest research results and conceptual understanding of fundamental mechanisms of protein, DNA and RNA methylation and demethylation, especially as relates to regulation of gene expression programs

  • Update on the current understanding of the role of biological methylation in human disease, especially cancer and inflammation

  • Presentations and workshops highlighting the latest technologies and methodologies for studying biological methylation in cells, tissues and organisms

Keynote Speakers

Kristian Helin, PhD
EMBO Keynote Lecture
University of Copenhagen

Tom Muir, PhD
Princeton University

Conference Organizers

Maria Elena Torres-Padilla, PhD
Helmholtz Zentrum M√ľnchen

Xiaobing Shi, PhD
The University of Texas M.D. Anderson Cancer Center

FASEB Conference Staff

Kristen Hagy, CMP, Conference Manager

Contact us

Email: src@faseb.org
Phone: 1.301.634.7010

Date & Location


June 17-22, 2018


Hilton Metropole Florence
Via del Cavallaccio, 36,
Florence, 50142, Italy

Transportation & Lodging

Airport Information

The Florence International Airport, A. Vespucci, or also known as Florence Peretola Airport (FLR) is 3 Km from the hotel. 

Please use the links below for Transportation & Lodging information:

Official Conference Lodging

Hilton Metropole Florence
Via del Cavallaccio, 36,
Florence, 50142, Italy

If you request a single or a double occupancy room, the registration fee covers 5 nights of lodging (Sunday through Thursday night, checkout Friday morning). A credit card will be required upon check-in for incidental expenses (i.e. in-room movies, room service, etc.).

If you plan to arrive early or stay beyond the conference dates, you must make your own reservations for the extra nights you require. You are responsible for payment upon check-out.

Click here for additional Offsite Lodging.

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