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Joseph C. LaManna, Ph.D. is Professor and Chair of the Anatomy Department at the Case Western Reserve University School of Medicine. He received his undergraduate degree in Biology at Georgetown University in Washington, DC in 1971. He received a PhD in Physiology and Pharmacology from Duke University in Durham, NC in 1975.
LaManna has been continuously funded by the National Institutes of Health, American Heart Association and other outside funding agencies since 1975 including an NIH (NINCDS) NRSA Post-doctoral Fellowship from 1975-1977, an (NHLBI) Young Investigator Award in 1977, and an NIH (NINCDS) Research Career Development Award from 1978-1981. His most recent NIH R01 renewal awarded is now in Years 6-10, and is entitled, “Brain vascular and metabolic adaptations to hypoxia”.
He has been involved in cerebrovascular research for more than 30 years. Research conducted in the laboratory is concerned with energy demand, energy metabolism, and blood flow in the brain. The role of these mechanisms in the tissue response to pathological insults such as stroke, cardiac arrest and resuscitation, and hypoxia is being actively investigated. His most recent research has centered on the role of hypoxia-inducible factor-1 induced angiogenesis in physiological adaptation to hypoxia and in neuroprotective and ischemic preconditioning. He has authored or co-authored over 200 research papers and review chapters.
LaManna is on the Editorial Boards of the Journal of Applied Physiology, Journal of Cerebral Blood Flow and Metabolism, and Brain Research. He is an active member of multiple scientific societies including the Society for Neuroscience (Program Committee 2002-2005); American Physiological Society; International Society for Oxygen Transport to Tissues (Executive Committee, 1986-89; 1995-98; 2000-03; President-Elect 2007); AAAS; International Society of Cerebral Blood Flow and Metabolism (Board of Directors, 2007-2011); Association of Anatomy, Cell Biology and Neuroscience Chairs (Executive Board 2002-06); American Association of Anatomists (Public Affairs Committee 1999 – 2007; Chair 2002 – 2007).
He was the recipient of the Jeanette M. and Joseph S. Silber Research Fund for the Study of Brain Sciences through Case Western Reserve University. He has participated in multiple grant reviews, study sections and site visits for NIH, NSF, AHA, VA, etc. as well as reviewing for the Ministry of Science and Technology of Portugal, Grant Agency of the Czech Republic, US-Israel Binational Science Foundation, The Wellcome Trust, and others. He served as a member of the NIH Neurology B-1 Study Section.
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